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The CIA continues a limited number of MKULTRA plans by beginning Project MKSEARCH to develop and test ways of using biological, chemical and radioactive materials in intelligence operations, and also to develop and test drugs that are able to produce predictable changes in human behavior and physiology (Goliszek).

Dr. Henry Beecher writes, "The well-being, the health, even the actual or potential life of all human beings, born or unborn, depend upon the continuing experimentation in man. Proceed it must; proceed it will. 'The proper study of mankind is man,'" in his "exposé" on human medical experimentation Research and the Individual ("Human Experimentation: Before the Nazi Era and After").

U.S. Army scientists drop light bulbs filled with Bacillus subtilis through ventilation gates and into the New York City subway system, exposing more than one million civilians to the bacteria (Goliszek).

The National Commission for the Protection of Research Subjects issues its Policies for the Protection of Human Subjects, which eventually creates what we now know as institutional review boards (IRBs) (Sharav).

(1967)
Continuing on his Dow Chemical Company-sponsored dioxin study without the company's knowledge or consent, University of Pennsylvania Professor Albert Kligman increases the dosage of dioxin he applies to 10 prisoners' skin to 7,500 micrograms, 468 times the dosage Dow official Gerald K. Rowe had authorized him to administer. As a result, the prisoners experience acne lesions that develop into inflammatory pustules and papules (Kaye).

The CIA places a chemical in the drinking water supply of the FDA headquarters in Washington, D.C. to see whether it is possible to spike drinking water with LSD and other substances (Cockburn and St. Clair, eds.).

In a study published in the Journal of Clinical Investigation, researchers inject pregnant women with radioactive cortisol to see if the radioactive material will cross the placentas and affect the fetuses (Goliszek).

The U.S. Army pays Professor Kligman to apply skin-blistering chemicals to Holmesburg Prison inmates' faces and backs, so as to, in Professor Kligman's words, "learn how the skin protects itself against chronic assault from toxic chemicals, the so-called hardening process," information which would have both offensive and defensive applications for the U.S. military (Kaye).

The CIA and Edgewood Arsenal Research Laboratories begin an extensive program for developing drugs that can influence human behavior. This program includes Project OFTEN -- which studies the toxicology, transmission and behavioral effects of drugs in animal and human subjects -- and Project CHICKWIT, which gathers European and Asian drug development information (Goliszek).

Professor Kligman develops Retin-A as an acne cream (and eventually a wrinkle cream), turning him into a multi-millionaire (Kaye).

Researchers paralyze 64 prison inmates in California with a neuromuscular compound called succinylcholine, which produces suppressed breathing that feels similar to drowning. When five prisoners refuse to participate in the medical experiment, the prison's special treatment board gives researchers permission to inject the prisoners with the drug against their will (Greger).

(1968)
Planned Parenthood of San Antonio and South Central Texas and the Southwest Foundation for Research and Education begin an oral contraceptive study on 70 poverty-stricken Mexican-American women, giving only half the oral contraceptives they think they are receiving and the other half a placebo. When the results of this study are released a few years later, it stirs tremendous controversy among Mexican-Americans (Sharav, Sauter).

(1969)
President Nixon ends the United States' offensive biowarfare program, including human experimentation done at Fort Detrick. By this time, tens of thousands of civilians and members of the U.S. armed forces have wittingly and unwittingly acted as participants in experiments involving exposure to dangerous biological agents (Goliszek).

The U.S. military conducts DTC Test 69-12, which is an open-air test of VX and sarin nerve agents at the Army's Edgewood Arsenal in Maryland, likely exposing military personnel (Goliszek, Martin).

Experimental drugs are tested on mentally disabled children in Milledgeville, Ga., without any institutional approval whatsoever (Sharav).

Dr. Donald MacArthur, the U.S. Department of Defense's Deputy Director for Research and Technology, requests $10 million from Congress to develop a synthetic biological agent that would be resistant "to the immunological and therapeutic processes upon which we depend to maintain our relative freedom from infectious disease" (Cockburn and St. Clair, eds.).

Judge Sam Steinfield's dissent in Strunk v. Strunk, 445 S.W.2d 145 marks the first time a judge has ever suggested that the Nuremberg Code be applied in American court cases (Sharav).

(1970)
A year after his request, under H.R. 15090, Dr. MacArthur receives funding to begin CIA-supervised mycoplasma research with Fort Detrick's Special Operations Division and hopefully create a synthetic immunosuppressive agent. Some experts believe that this research may have inadvertently created HIV, the virus that causes AIDS (Goliszek).

Under order from the National Institutes of Health (NIH), which also sponsored the Tuskegee Experiment, the free childcare program at Johns Hopkins University collects blood samples from 7,000 African-American youth, telling their parents that they are checking for anemia but actually checking for an extra Y chromosome (XYY), believed to be a biological predisposition to crime. The program director, Digamber Borganokar, does this experiment without Johns Hopkins University's permission (Greger, Merritte, et al.).

(1971)
President Nixon converts Fort Detrick from an offensive biowarfare lab to the Frederick Cancer Research and Development Center, now known as the National Cancer Institute at Frederick. In addition to cancer research, scientists study virology, immunology and retrovirology (including HIV) there. Additionally, the site is home to the U.S. Army Medical Research Institute, which researches drugs, vaccines and countermeasures for biological warfare, so the former Fort Detrick does not move far away from its biowarfare past (Goliszek).

Stanford University conducts the Stanford Prison Experiment on a group of college students in order to learn the psychology of prison life. Some students are given the role as prison guards, while the others are given the role of prisoners. After only six days, the proposed two-week study has to end because of its psychological effects on the participants. The "guards" had begun to act sadistic, while the "prisoners" started to show signs of depression and severe psychological stress (University of New Hampshire).

An article entitled "Viral Infections in Man Associated with Acquired Immunological Deficiency States" appears in Federation Proceedings. Dr. MacArthur and Fort Detrick's Special Operations Division have, at this point, been conducting mycoplasma research to create a synthetic immunosuppressive agent for about one year, again suggesting that this research may have produced HIV (Goliszek).

(1972)
In studies sponsored by the U.S. Air Force, Dr. Amedeo Marrazzi gives LSD to mental patients at the University of Missouri Institute of Psychiatry and the University of Minnesota Hospital to study "ego strength" (Barker).

(1973)
An Ad Hoc Advisory Panel issues its Final Report on the Tuskegee Syphilis Study, writing, "Society can no longer afford to leave the balancing of individual rights against scientific progress to the scientific community" (Sharav).

(1974)
Congress enacts the National Research Act, creating the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research and finally setting standards for human experimentation on children (Breslow).

(1975)
The Department of Health, Education and Welfare gives the National Institutes of Health's Policies for the Protection of Human Subjects (1966) regulatory status. Title 45, known as "The Common Rule," officially creates institutional review boards (IRBs) (Sharav).

(1977)
The Kennedy Hearing initiates the process toward Executive Order 12333, prohibiting intelligence agencies from experimenting on humans without informed consent (Merritte, et al.).

The U.S. government issues an official apology and $400,000 to Jeanne Connell, the sole survivor from Col. Warren's now-infamous plutonium injections at Strong Memorial Hospital, and the families of the other human test subjects (Burton Report).

The National Urban League holds its National Conference on Human Experimentation, stating, "We don't want to kill science but we don't want science to kill, mangle and abuse us" (Sharav).

(1978)
The CDC begins experimental hepatitis B vaccine trials in New York. Its ads for research subjects specifically ask for promiscuous homosexual men. Professor Wolf Szmuness of the Columbia University School of Public Health had made the vaccine's infective serum from the pooled blood serum of hepatitis-infected homosexuals and then developed it in chimpanzees, the only animal susceptible to hepatitis B, leading to the theory that HIV originated in chimpanzees before being transferred over to humans via this vaccine. A few months after 1,083 homosexual men receive the vaccine, New York physicians begin noticing cases of Kaposi's sarcoma, Mycoplasma penetrans and a new strain of herpes virus among New York's homosexual community -- diseases not usually seen among young, American men, but that would later be known as common opportunistic diseases associated with AIDS (Goliszek).

(1979)
The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research releases the Belmont Report, which establishes the foundations for research experimentation on humans. The Belmont Report mandates that researchers follow three basic principles: 1. Respect the subjects as autonomous persons and protect those with limited ability for independence (such as children), 2. Do no harm, 3. Choose test subjects justly -- being sure not to target certain groups because of they are easily accessible or easily manipulated, rather than for reasons directly related to the tests (Berdon).

(1980)
A study reveals a high incidence of leukemia among the 18,000 military personnel who participated in 1957's Operation Plumbbob (a href="http://en.wikipedia.org/wiki/Operation_Plumbbob">"Operation Plumbob").

According to blood samples tested years later for HIV, 20 percent of all New York homosexual men who participated in the 1978 hepatitis B vaccine experiment are HIV-positive by this point (Goliszek).

American http://www.newstarget.com/doctors.html>doctors give experimental hormone shots to hundreds of Haitian men confined to detention camps in Miami and Puerto Rico, causing the men to develop a condition known as gynecomastia, in which men develop full-sized breasts (Cockburn and St. Clair, eds.).

The CDC continues its 1978 hepatitis B vaccine experiment in Los Angeles, San Francisco, Chicago, St. Louis and Denver, recruiting over 7,000 homosexual men in San Francisco alone (Goliszek).

The FDA prohibits the use of prison inmates in pharmaceutical drug trials, leading to the advent of the experimental drug testing centers industry (Sharav).

The first AIDS case appears in San Francisco (Goliszek).