Monday, September 15, 2008

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Pregnant women plagued by cravings for pickles and ice cream must remember to include plenty of folic acid in their diets. Shown to reduce the risk of miscarriage and birth defects, folic acid – found primarily in leafy green vegetables – is an absolute necessity for any woman who is pregnant or is considering becoming pregnant. In fact, "health officials at the U.S. Centers for Disease Control and Prevention (CDC) now recommend that all women of childbearing age take folic acid (0.4 mg daily) to protect their future newborns from developing a neural tube defect, an anomaly of the spinal cord," writes Burton Goldberg in Alternative Medicine.

However, it's not just expectant moms who could stand to add more leafy greens to their plates. Because it is useful in combating everything from acne and canker sores to osteoporosis and cancer, we could all benefit from adding more folic acid to our diets. Along with pregnant women, elderly individuals and people suffering from depression or nervous system disorders especially stand to gain from the addition of this B vitamin.

Folic acid, the synthetic form of the B vitamin folate, works primarily in the brain and nervous system and is necessary for the synthesis of DNA, the production of red and white blood cells and of norepinephrine and serotonin in the nervous system. Folic acid also aids in the elimination of the amino acid homocysteine from the blood, a breakdown product of animal protein (methionine, actually) that contributes to heart attacks. A lack of folic acid can lead to anemia, insomnia, irritability and far more serious health problems.

Despite its range of health benefits, many Americans are deficient in the vitamin, coming nowhere near the government's recommended daily allowance of 200 micrograms daily. "The average American gets only 61 percent of the old Recommended Dietary Allowance, which is too low anyway," says James Duke, PhD in Anti-Aging Prescriptions. Part of the reason for the shortfall is that more Americans are choosing to eat more animal foods – which are a poor source of folic acid – rather than folic-acid rich plant foods, like dark green vegetables, legumes, root vegetables and whole grains.

Dr. Andrew Weil, in Ask Dr. Weil, recommends the use of supplements to make up for the deficiency. "As many as 90 percent of Americans don't get that protective 400 micrograms in their diet – for example, you'd have to eat two cups of steamed spinach, a cup of boiled lentils, or eight oranges every day. So it's important to take a supplement, especially if you're a woman and considering having children someday." As Dr. Weil suggests, for women who are deficient in this essential vitamin, the health costs can be especially high.

Folic acid is essential for pregnant women. Not only does it protect against cervical cancer, it also aids in healthy prenatal development and can significantly reduce the risk of serious neural tube birth defects and abnormalities that occur in very early fetal development, such as spina bifida. However, experts say most women aren't getting adequate levels of folic acid early enough to offer the best protection against birth defects.

"Very few women of child bearing years are taking folic acid… If a person waits until pregnant, the fetal abnormality is already established. All women of child-bearing age who might become pregnant should be taking 400 mg of folic acid," advises Dr. James Howenstine in A Physicians Guide To Natural Health Products That Work. To make matters even more difficult, women who take birth control pills are especially prone to deficiency in the B vitamin since birth control pills actually produce folic acid deficiency.

Men planning to become fathers need to monitor their folic acid intake as well, as low folic acid levels in males has been linked to low sperm count, and some studies suggest deficiency can also damage DNA carried by the sperm. Such damaged DNA could lead to chromosomal damage in a fetus, according to Bottom Line Yearbook 2004. In other words, both men and women who plan to have children should increase their folic acid intake for the sake of their baby-to-be.

Folic acid promotes good health for the mind and body, from the earliest stages of life to the latest. Men and women over 60 who feel fatigued and depressed may simply be suffering from a folic acid deficiency. In fact, folic acid deficiency has been linked to depression in patients of all ages, and according to Gary Null'sComplete Guide of Natural Healing, "the lower the level of folic acid in the blood, the higher the degree of depression."

Folic acid can also help ward off dementia, according to Patrick Quillin in Beating Cancer With Nutrition, who wrote that experts estimate up to 20 percent of senility in older adults is simply the result of a long-term deficiency of folic acid and vitamin B-12, which can be aided by taking supplements. However, when taking folic acid supplements, it is important to remember that folic acid and vitamin B-12 work most effectively together, so you should make sure you are getting enough vitamin B-12, as well. Vegans often struggle with this balance since their diets are very rich in folic acid but not in B-12.

The meager representation of folic acid in the American diet can be increased if we all just take a little more care in planning our meals. One way to up folic acid consumption is to make sure your diet includes raw foods, since heat from cooking easily destroys folic acid. And remember, sources of folic acid are plentiful – soybeans, spinach, broccoli, cabbage, peanuts, asparagus, citrus fruits, brussels sprouts, avocado, sunflower seeds, orange juice and don't forget those leafy greens – we just have to be willing to integrate these foods into our diets.

And who wouldn't be willing? After all, some added folic acid could go a long way in helping keep your nervous and circulatory systems in check, while also protecting your body from cancer and heart problems, as well as promoting healthy fetal development in babies. Folic acid is something we need at all stage of life, so we owe it to ourselves to get enough.

The experts speak on folic acid

General information on folic acid
A study is available from the Washington Council for Responsible Nutrition that reports women taking Vitamin E over age 50 and folic acid and Zinc during childbearing years would save Medicare 11 billion dollars, and overall reduce birth defects and coronary heart disease hospital expenses of 20 billion dollars per year.
Anti-Aging Manual by Joseph B Marion, page 100

WHAT IS IT? Even though your body needs only comparatively minuscule amounts of folic acid, it is a vital nutrient. Folic acid—along with all the other nutrients, of course—is your guarantee of optimum physical and mental health. Your levels of folic acid are dependent on outside sources; your body does not make it on its own. Furthermore, it needs vitamin C to work properly. It works in partnership with B12 and B6, as well as the other B vitamins. Folic acid is essential to the production of norepinephrine and serotonin, chemical go-betweens of the nervous system.
Complete Guide Health Nutrition by Gary Null, page 284

Folic acid is one of the B vitamins that is crucial for the synthesis of DNA (genetic material) as well as for many other important cell functions. It was discovered in spinach leaves in 1941 and was named "folate," after the Latin word for leaf (folium). The terms folate and folic acid are roughly synonymous. For the sake of simplicity, I will generally use the latter term. Not surprisingly, this vitamin is mainly found in green leafy vegetables. Although folic acid is not an antioxidant, it boosts the antioxidant network and thus has a place in our story.
Antioxidants Against Cancer by Ralph Moss PhD, page 92

WHO NEEDS folic acid? If you are pregnant, elderly, or suffer from any sort of nervous disorder, you may benefit from additional amounts of folic acid in your diet. Pregnant women, for instance, must be wary of folic acid deficiency. Folic acid supplementation has been helpful in preventing abortion and miscarriage. The elderly need additional folic acid, too. If you are over sixty and depressed, withdrawn, and chronically tired, you may be deficient in this vital element. Let's look at the results of a study in which folic acid was added to the diets of elderly individuals: three groups of patients were used, all with varying degrees of circulation problems. The first group, those with the least degree of difficulty, experienced improved vision less than an hour after receiving folic acid. (Among those with circulatory problems, vision is often impaired because of poor circulation to the optical tissues.)
Complete Guide Health Nutrition by Gary Null, page 284

Folic acid: a water-soluble vitamin of the B complex essential for the synthesis of nucleic acids and necessary for making red blood cells (hematopoiesis), so a deficiency of folic acid results in anemia. After absorption, it is successively reduced to dihydro-folic acid and then tetrahydrofolic acid, the parent compound of the derivatives that act as coenzyme carriers of one-carbon groups in various metabolic reactions.
Building Wellness with DMG by Roger V Kendall PhD, page 216

Red blood cells are built with Vitamins B-12, folic acid, and B6.
Anti-Aging Manual by Joseph B Marion, page 100

And remember, folic acid can be destroyed by exposure to heat and strong light.
Complete Guide Health Nutrition by Gary Null, page 286

Recommendations on folic acid
Doctors routinely advise women who are pregnant, or thinking of becoming pregnant, to supplement folic acid (a B vitamin also known as folate) as a means of safeguarding against birth defects such as spinal malformations.
Anti-Aging Prescriptions by James Duke PhD, page 219

It is becoming increasingly obvious that food supplementation is necessary to prevent cancer and other diseases. The prestigious Institute of Medicine (IOM) of the National Academy of Sciences in 1998 called for supplementation with folic acid and vitamin B12.
Antioxidants Against Cancer by Ralph Moss PhD, page 10

If you're concerned that your diet might not provide enough vitamin B6 and folic acid to prevent stroke, Dr. Lieberman suggests taking supplements of both nutrients. Aim for 300 milligrams of B6 and 800 micrograms of folic acid a day Vitamin B6 doses this high, however, should only be taken under medical supervision. Add E for extra protection.
Blended Medicine by Michael Castleman, page 10

Vegetarians owe it to themselves to be extra careful about their diets. As Richard W. Vilter, M.D., of the University of Cincinnati College of Medicine, warns, "Persons who eat absolutely no animal protein (called vegans) or extreme vegetarians have no source of vitamin B12, but much folic acid in their diets." Frequently in such subjects, neurologic abnormalities develop of the posterolateral column degeneration type. This is a situation analogous to a patient with pernicious anemia who is treated inadequately with a mixed vitamin capsule containing folic acid." There is another danger for those who abstain from animal foods, including dairy products: dietary deficiencies don't show up for five to ten years because the body is able to hold some B12 in reserve. Nerve damage may exist without signs of deficiency until it is too late. The result of degeneration of the nervous system and the spinal cord is so irreparable that death may be the result.
Complete Guide Health Nutrition by Gary Null, page 283

Benefits and uses of folic acid
Folic acid is important during the aging process because it provides nourishment for the brain. Folic acid supports the production of energy and the production of blood cells. Supplementing with folic acid may help in the treatment of depression.
Alternative Medicine by Burton Goldberg, page 321

Three to four hundred milligrams of vitamin B5 and 150 mg of B6 should be consumed on a daily basis, while prescriptions of folic acid can serve as natural hormone replacements. Adequate quantities of essential fatty acids should also be consumed because they act as natural hormone supplements, prevent cancer, and can alleviate the symptoms of aging.
Complete Encyclopedia Of Natural Healing by Gary Null PhD, page 258

Folic acid, the synthetic form of the B vitamin folate, is incredibly important. For one thing, folate is a key regulator of an amino acid called homocysteine, a breakdown product of animal protein. A number of studies have connected high levels of homocysteine in the blood to arterial disease and heart attacks. Folate helps the body eliminate homocysteine from the blood. Recently, Dr. Howard Morrison, an epidemiologist in Ottawa, was able to make a direct connection between folate and heart disease. He looked at folate levels in the blood of 5,056 men who had participated in a nutrition study in the 1970s, and he found that those with low levels of the vitamin were 69 percent more likely to have died from heart problems in the years since. Folate also has been found to prevent neural tube defects (such as spina bifida and anencephaly) in babies, which are caused when this structure fails to form properly. The neural tube is the embryonic tissue that later becomes the brain and spinal cord. Apparently folic acid is essential to its proper development. Earlier this year, the Food and Drug Administration ordered pasta, rice, and flour makers to add folic acid to their foods as protection against birth defects.
Ask Dr Weil by Andrew Weil MD, page 98

Proper nutritional supplementation can significantly improve cardiovascular conditions, as well as prevent them from occurring in the first place. Useful nutrients include beta carotene; vitamins B3 (niacin), Be, B12, C, and E; folic acid; the minerals calcium, chromium, magnesium, potassium, and selenium; the amino acids L-arginine, L-taurine, and L-carnitine; coenzyme Q10; and pycnogenol.
Alternative Medicine by Burton Goldberg, page 771

According to some studies, folic acid has been helpful in relieving depression, even when used in dosages as low as 400 meg. It can also enhance cerebral circulation. One study showed that people with low levels of folic acid were twice as likely as people with adequate levels to have narrowed arteries in their necks. Psychiatric symptoms also appear to be much higher in people, particularly elderly people, who have low folic acid levels. In one study, low folic acid levels increased likelihood of dementia by 300 percent. folic acid is especially effective at breaking down the common chemical homocysteine, which is a neurotoxin. An appropriate daily dosage would be 400 meg, the amount found in many multiple vitamins.
Brain Longevity by Dharma Singh Khalsa M.D. with Cameron Stauth, page 247

Folic acid: This is another member of the vitamin B family, found in abundance in liver, kidney, mushrooms, spinach, yeast and green leafy vegetables. It has been used for decades to prevent and treat certain forms of anemia. But folic acid also increases the production of white blood cells crucial in the defense against cancer. In the late 1980s, scientists at the University of Alabama Medical Center found that the folic acid in dark leafy vegetables, oranges and liver could act together with vitamin B to prevent injuries to lung tissue and retard the development of cancer among cigarette smokers. These researchers found that smokers whose lung cells were injured had low levels of both folic acid and vitamin B12. Since these nutrients are necessary to synthesize DNA, a deficiency of one or both of these vitamins could make cells more susceptible to the effects of carcinogens. These vitamins also offered protection against birth defects and cancerous changes in cervical cells.
Cancer Therapy by Ralph W Moss PhD, page 42

Floss one to two times daily and then rinse mouth (for one minute) with several mouthfuls of liquid folic acid (0.1% solution) and then swallow. In one study, 60 individuals with gingivitis rinsed for one minute two times daily and had beneficial results. If you cannot find liquid folic acid, buy folic acid crystals in 800 meg capsules, empty two capsules in water and use this to gargle.
Alternative Medicine by Burton Goldberg, page 1055

Lipotropic factors are compounds that promote the transportation and utilization of fats, and help prevent the accumulation of fat in the liver. They include methionine, choline, folic acid, and vitamin B12.
Cancer And Natural Medicine by John Boik, page 140

Folic acid helps against uric acid.
Anti-Aging Manual by Joseph B Marion, page 560

The four B vitamins that are most important for your brain are B12, B6, B3, and folic acid.
Brain Longevity by Dharma Singh Khalsa M.D. with Cameron Stauth, page 246

The body uses 75-99% of its Calcium, with Phosphorus, Boron, Manganese, Silica, Magnesium, Copper, Zinc, Strontium; Protein; the Vitamins A, B-Complex, B6, folic acid, Vitamin C, Vitamin D, and Vitamin K to form bone tissue and teeth.
Anti-Aging Manual by Joseph B Marion, page 800

The primary nutritional building blocks of both neurotransmitters are the amino acids tyrosine and phenylalanine. To potentiate the action of these amino acids, folic acid, magnesium, and vitamins C and B can be taken.
Brain Longevity by Dharma Singh Khalsa M.D. with Cameron Stauth, page 213

Part of the vitamin B complex, folic acid is necessary for synthesis of nucleic acids and formation of the heme component of hemoglobin in red blood cells.

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